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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. Fantastic value for the money. Exceptionally clean room and linens. The A/C is working perfectly, all the amenities are in excellent condition. The staff provided professional and courteous service.

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9
Wonderful
835 reviews
Price from
$50.16
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Perfect location in the best area full of restaurants and close to the big mall, lovely staff, fantastic breakfast and amazing swimming pool on the top.

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9
Wonderful
413 reviews
Price from
$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Incredible location and stunning, quirky architecture. Staying at this hotel is an experience in itself

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9.2
Wonderful
250 reviews
Price from
$42.75
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. How we were welcomed by the receptionist Marcela. How Fabricio the bar tender was attentive and eager to please. How Rodrigo was great in the morning during breakfast. Just perfect. Thank you so much for this amazing experience. And again thank you to these three people mentioned above. They deserved to be rewarded.

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9.1
Wonderful
303 reviews
Price from
$118.40
per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Outstanding service in clean open friendly space. Central location. Arrived during strikes so very little open.

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9.1
Wonderful
865 reviews
Price from
$84.36
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Beautiful place! Really quiet and relaxing and the staff was so helpful and kind. Can't recommend this place enough and we look forward to come back!

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9.3
Wonderful
119 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. El Pueblito is a representation of a small town, each room representing parts if the town with exquisite decoration. You have a carpentry, bank, florist, artist’ house, chapel, etc… the view is magnificent. El Pueblito is a nice quiet place to relax. The food is very good as well. The family that owns and runs the hotel is very attentive and warm. 100% recommended!

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9.5
Exceptional
222 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Enormous space, views from the terraces, breakfast was superb, most staff friendly and helpful. Not much I can say against this place. One of the nicest and best value places I’ve stayed in in Latin America, and I’ve notched up a good few.

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9.4
Wonderful
377 reviews
Price from
$94.50
per night

Hotel Lido

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 7-minute walk from 24th of September Metropolitan Plaza, Hotel Lido has accommodations with a terrace, free private parking and a restaurant.

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9
Wonderful
5 reviews
Price from
$39.54
per night

Rústico & Hotel Boutique Las Churapas

Hotel in San José de Chiquitos

Rústico & Hotel Boutique Las Churapas features an outdoor swimming pool, garden, a terrace and bar in San José de Chiquitos. The hotel provides both free WiFi and free private parking. The people running this hotel are simply amazing. Kind, helpful and ready with information on the town. During heavy rain they even took us by car to the city centre. What a amazing welcome for us in Bolivia. Room is also very nice and clean with a good bed and good shower. Pool was a bit cold, but great refresher on hot days. If you want to visit Kaa Iya National Park, this is a great place for your tour to start and end.

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9.2
Wonderful
83 reviews
Price from
$38
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Cleanliness & disinfection
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Most-booked hotels in Santa Cruz Region in the past month

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Santa Cruz Region's best hotels with breakfast

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